Adacel
This vaccine protects against diphtheria, tetanus, and pertussis.
Ingredients:
Active ingredients:
Tetanus toxoid, diphtheria toxoid, detoxified pertussis toxin, filamentous hemagglutinin (a cell surface protein), pertactin (outer membrane protein), and fimbriae types 2 and 3 (parts of the bacterium that allow it to attach to host cells)
Inactive ingredients:
Amounts are based on a 0.5 mL dose
Adjuvants: strengthen the immune response to the vaccine
Other:
Relevant Terms:
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Antibiotics: substances that kill bacteria or prevent them from dividing. Antibiotics are used in some vaccines to prevent contamination during the manufacturing process
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Antibody: a protein made by the immune system in response to a foreign particle (antigen). These proteins circulate in the blood and help defend the body against the substance
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Antigen: This is any substance that triggers the immune system to create antibodies. For example, allergens such as pollen are antigens
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Antitoxin: an antibody that neutralizes toxins
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Bacterium: The singular of bacteria (one bacterium, two bacteria)
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Toxoid: an inactive version of a toxin produced by a bacterium. The body is able to make antitoxin without being exposed to the actual toxin. Toxoids are not toxic.
Sources
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Package insert: https://www.fda.gov/media/119862/download?attachment
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General:
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Toxoid: https://www.sciencedirect.com/topics/neuroscience/toxoid
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Antibiotics:
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Aluminum:
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Aluminum phosphate:
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Formaldehyde: https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-ingredients/formaldehyde
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Glutaraldehyde:
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2-phenoxyethanol: https://pubchem.ncbi.nlm.nih.gov/compound/2-Phenoxyethanol​​
Last updated: July 26, 2024