PedvaxHIB
This is a Haemophilus influenzae type B (Hib) vaccine.
Ingredients:
Active ingredients:
The active ingredient is a purified sugar from the capsule (outer layer) of the Haemophilus influenzae type B bacterium. This sugar is conjugated (attached) to a protein from the outside of the bacterium Neisseria meningitidis to improve the immune response to the sugar. Because there are only pieces of these bacteria, you cannot get infected with either bacterium from the vaccine.
Inactive ingredients:
Amounts are based on a 0.5 mL dose
Salts: help maintain the stability and pH of the vaccine
Adjuvants: strengthen the immune response to the vaccine
Relevant Terms
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Antibody: a protein made by the immune system in response to a foreign particle (antigen). These proteins circulate in the blood and help defend the body against the substance.
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Antigen: This is any substance that triggers the immune system to create antibodies. For example, allergens such as pollen are antigens.
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Bacterium: the singular of bacteria (one bacterium, two bacteria)
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Conjugate: An antigen is attached to a protein in order to improve the protection the vaccine provides.
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pH: a measure of how acidic or basic a solution is. The scale ranges from 0 (very acidic) to 14 (very basic). A pH of 7 is neutral.
Sources
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General:
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Aluminum:
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Salt: https://www.health.harvard.edu/newsletter_article/sodium-salt-and-you
Last updated: Feb. 20, 2023