Active ingredients:
Prehevbrio
This is one of the hepatitis B vaccines
Ingredients:
Active ingredients:
Three Hepatitis B surface antigens, which are proteins on the surface of the virus.
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This is a recombinant protein vaccine, which means that the instructions to make these surface antigens are inserted into the genome of cells so that they produce the proteins.
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Note: this vaccine contains trace amounts of DNA and proteins from the cells used to produce the surface antigen. These cells are Chinese hamster ovary cells.
Inactive ingredients:
Adjuvants:Â strengthen the immune response to the vaccine
Salts: help maintain the stability and pH of the vaccine
Ingredients from Manufacturing:
Relevant Terms
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Antibody: a protein made by the immune system in response to a foreign particle (antigen). These proteins circulate in the blood and help defend the body against the substance.
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Antigen: This is any substance that triggers the immune system to create antibodies. For example, allergens such as pollen are antigens.
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Genome: all of the genetic information in a cell
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pH: a measure of how acidic or basic a solution is. The scale ranges from 0 (very acidic) to 14 (very basic). A pH of 7 is neutral.
Sources
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Package insert: https://www.fda.gov/media/154561/download
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​General:​
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Aluminum:
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Aluminum Hydroxide: https://medlineplus.gov/druginfo/meds/a601013.html
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Sodium chloride: https://www.health.harvard.edu/newsletter_article/sodium-salt-and-you
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Sodium phosphate:
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Potassium phosphate:
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Potassium chloride:
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Formaldehyde: https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-ingredients/formaldehyde
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Bovine serum albumin:
Last updated: Feb. 20, 2023