Quadracel
This vaccine protects against diphtheria, tetanus, pertussis, and polio
Ingredients:
Active ingredients:
Diphtheria toxoid, tetanus toxoid, detoxified pertussis toxin, inactivated polioviruses types 1, 2, and 3, filamentous hemagglutinin (a cell surface protein), pertactin (outer membrane protein), and fimbriae types 2 and 3 (parts of the bacterium that allow it to attach to host cells)
Inactive ingredients:
Amounts are based on a 0.5 mL dose
Carbohydrates: normally used as stabilizers in vaccines
Adjuvants: strengthen the immune response to the vaccine
Antibiotics: used to prevent contamination during manufacturing
Growth agents: ingredients that help the active ingredients grow in order to make the vaccine
Other:
Relevant Terms:
-
Antibiotics: substances that kill bacteria or prevent them from dividing. Antibiotics are used in some vaccines to prevent contamination during the manufacturing process
-
Antibody: a protein made by the immune system in response to a foreign particle (antigen). These proteins circulate in the blood and help defend the body against the substance
-
Antigen: This is any substance that triggers the immune system to create antibodies. For example, allergens such as pollen are antigens
-
Antitoxin: an antibody that neutralizes toxins
-
Bacterium: The singular of bacteria (one bacterium, two bacteria)
-
Carbohydrates: This is another word for sugars
-
Emulsifier: a substance that helps to keep the ingredients mixed together
-
Toxoid: an inactive version of a toxin produced by a bacterium. The body is able to make antitoxin without being exposed to the actual toxin. Toxoids are not toxic.
Sources:
-
Package insert: https://www.fda.gov/media/91640/download
-
General:
-
Hemagglutinin: https://pubmed.ncbi.nlm.nih.gov/2294058/
-
Toxoid: https://www.sciencedirect.com/topics/neuroscience/toxoid
-
Aluminum:
-
Aluminum phosphate:
-
Sugar:
-
Bovine serum albumin:
-
Formaldehyde: https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-ingredients/formaldehyde
-
Polysorbate-80:
-
Neomycin: ​​
-
Polymyxin B Sulfate:
-
Glutaraldehyde:
-
2-phenoxyethanol: https://pubchem.ncbi.nlm.nih.gov/compound/2-Phenoxyethanol
Last updated: July 10, 2023